-
Join 20 other subscribers
Categories
- ADME
- Bioactivation
- Biotransformation
- Blood Brain Barrier
- Carcinogens
- Central Nervous System (CNS)
- Chemistry
- Company
- Conjugation Reactions
- Covalent Binding
- Cytochrome P450
- Definitions
- Disease
- DNA Adducts
- Drug Design
- Drug Drug Interaction (DDI)
- Drug Metabolism
- Drug Safety
- Drug Target
- Drugs
- Heterocycles
- Human Liver Microsomes(HLM)
- Idiosyncratic Effect
- Immune Response
- In Vitro/In Vivo Correlation
- Introduction
- Mass Spectrometry
- Mechanism-Based Inhibition (MBI)
- Med Chem
- Metabolic Stability
- Metabolite Identification (MetID)
- Metabolite Prediction
- Metabolite Profiling
- Metabolomics
- Mutagens
- Natrual Products
- Non-P450 enzymes
- P450 Phenotyping
- Pharmacokinetics (PK)
- Phase 2 Metabolism
- Physicochemical Properties
- Protein Adducts
- Radioisotope Label
- Reactive Intermediates
- SAR
- Solvent Effects
- Time-dependent Inhibition (TDI)
- Toxicity
- Uncategorized
Recently Viewed Posts
- Metabolically Stable tert-Butyl Replacement ACS Med Chem Lett 2013
- Deuterated Clopidogrel Analogues as a New Generation of Antiplatelet Agents ACS Med Chem Lett 2013
- Thiolactone Sulfoxides as New Reactive Metabolites Acting as Bis-Electrophiles: Implication in Clopidogrel and Prasugrel Bioactivation CRT 2013
- Which Metabolites Circulate? Minireview DMD 2013
- Boronic Acid-Containing Proteasome Inhibitors: Alert to Potential Pharmaceutical Bioactivation CRT 2013
Blogs I Follow
Daily Archives: January 7, 2013
Principles and Applications of Halogen Bonding in Medicinal Chemistry and Chemical Biology JMC 2012
Wilken, R., et al. J. Med. Chem., 2013, 56 (4), pp 1363–1388
Posted in Drug Design, Halogen Bonding, Med Chem
Tagged Drug Design, Halogen Bonding, Med Chem, Review
Leave a comment
Organosilicon Molecules with Medicinal Applications JMC 2012
Franz, A. K. and Wilson, S. O. J. Med. Chem., 2013, 56 (2), pp 388–405
ADMETchemist 