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Blogs I Follow
Category Archives: 1A1
The role of biotransformation enzymes in the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions and difficult answers. 2009
Stiborova M., Frei E., Arlt V.M., Schmeiser H.H. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2009 Mar;153(1):5-11. Enzymes may be involved in the bioactivation of AA include NAD(P)H:quinone oxidoreductase (NQO1), followed by cytochrome P450 (CYP) 1A1/2 in hepatic microsomes, and NADPH:CYP reductase … Continue reading
3-Methylindole Metabolites Induce Lung CYP1A1 and CYP2F1 Enzymes by AhR and Non-AhR Mechanisms, Respectively
Weems, J. M., et al. Chem. Res. Toxicol., 2010, 23 (3), pp 696–704
ADMETchemist 